SERUM TOTAL OXIDATIVE AND ANTIOXIDATIVE STATUS IN PATIENTS WITH POSTMENOPAUSAL OSTEOPOROSIS

Abstract

Objective: The aim of this study was to investigate and compare the relationship between serum oxidative/anti-oxidative capacity, oxidative stress and bone mineral density in patients with postmenopausal osteoporosis and in healthy controls. Material and Method: 119 female cases (60 patients and 59 controls) were included in this study. Oxidative status were measured by Erel's method. Results: There was no statistically significant difference between two groups for total oxidative capacity (p > 0.05); however, total anti-oxidative capacity was significantly lower in the patient group than that in controls (p < 0.00l). Conclusion: Total antioxidant capacity is negatively affected in patients with postmenopausal osteoporosis. Antioxidant treatment with diet can contribute to support osteoporosis.