Neurofibromatosis and Pregnancy

Abstract

Neurofibromatosis (NF) is an autosomal dominant genetic syndrome which can be seen in 1:3000-1:5000 women. Women with NF without infertility problem may have one or more pregnancies during reproductive years. Pregnancies of patients with neurofibromatosis are known to be complicated by intrauterine growth retardation, preterm birth, gestational hypertension and preeclampsia, but history of abruption is very rare in few cases. Physicians should be aware of the complications of this unique pregnancy and manage it multidisciplinary. The purpose of this case report is to share the experience of the pregnancy with neurofibromatosis, having epilepsy and unexplained embolism history, which is complicated with intrauterine growth retardation and placental abruption