POSTPARTUM RESOLUTION TIME OF PROTEINURIA IS A GOOD PREDICTOR FOR POOR MATERNAL OUTCOMES IN PREECLAMPSIA

Abstract

Objective: In this study, we aimed to define the mean resolution time of proteinuria in postpartum pregnant women with preeclampsia and to investigate the relationship between resolution time and the poor obstetric outcomes. Material and Method: The research was conducted as a retrospective, descriptive, cross-sectional study by evaluation of the medical records. Women with preeclampsia were divided into two subgroups: Severe preeclampsia (SPE) and non severe preeclampsia (NSPE). Results: The mean resolution time of proteinuria was 3 days; 3.5 days in the SPE group and 2.1 days in the NSPE group (p=0.002). The resolution time of proteinuria had a good predictive value for poor maternal outcome with an ROC-AUC of 0.73 (95% CI 0.59-0.88; p=0.002), the sensitivity and specificity were 62.5% and 80.2%, respectively. Proteinuria lasted longer than 3 days related with a higher risk of poor maternal outcomes. The ROC-AUC value of the resolution time of proteinuria for severe preeclampsia was found to be 0.70 (95% CI 0.61-0.80; p = 0.001). The sensitivity and specificity were 72.1% and 63.5%, respectively. Amount of proteinuria at diagnosis had a statistically significant relationship with the presence of proteinuria at discharge (OR 2.70; 97.5% CI 1.32-6.02; p = 0.0096). Conclusion: Our results, show that the resolution time of proteinuria at the puerperal period has a predictive value for poor maternal outcomes.