Current trends of computational tools and artificial intelligence in geriatric medicine

Abstract

As lifespans grow across the globe, so does the prevalence of neurodegenerative diseases among a rapidly expanding elderly demographic. Originating in the brain—the least understood organ in the human body—neurodegenerative diseases are caused by complex mechanisms that are challenging to study in a heterogeneous patient population. Machine learning, natural language processing, and other subfields of artificial intelligence have shown great promise as computational tools enabling physician-scientists to tackle these challenges on a potentially large scale. This chapter explores current applications of artificial intelligence in the classification, treatment, and management of the most common neurodegenerative diseases. © 2025 Elsevier Inc. All rights reserved.