Comparison of Crp and Ferritin Levels in Preterm Labor and Premature Membrane Ruptured Cases

Abstract

Aim: Premature ruptur of membranes (PROM) means the rupture of membranes at least one hour before the active labor begins. It is named as pre-term premature rupture of membranes(PretermPROM) if the rupture occurs before the 37th weeks of gestation. Although the etiologies, complications and results of the PROM and PretermPROM are similar, it has been showed that the major reason for the PretermPROM is infection in choriodesidual unit. Material and Method: It is important to identify the maternal infection for protection against the negative outcomes of prematurity and preterm labor. To obtain the probable maternal infection we can use serum markers of inflamation like leucocyte count, C-reactive protein, ALP, beta-2 microglobulin, alfa-2 macroglobulin. Results: We observed the serum levels of CRP and ferritin in PROM and PretermPROM diagnosed patients. The aim of this trial was to asses the differences of serum CRP and fibrinogen consantrations in selected PROM and PretermPROM diagnosed cases to emphasize the importance of subclinical infection in these diseases. Discussion: According to the results of our trial we found that CRP levels were in normal range in control group but significantly higher in group with PROM and Preterm PROM. In groups with PROM and Preterm PROM avarege value of ferritin was significantly higher than control group. Present results supports that serum ferritin and CRP levels are useful for follow-up possible infections in pregnant women with PROM and Preterm PROM.