Comparison of several anthropometric measurements and blood lipid-related indexes in metabolic-dysfunction associated fatty liver disease in adults: A cross-sectional study

Abstract

Dyslipidemia is strongly related to metabolic-dysfunction associated fatty liver disease (MAFLD). Therefore, the lipid profile may be a potential indicator of defining MAFLD. Anthropometric measurements are widely used as simple and practicable tools to screen metabolic dysfunction, and no study determined the relationship between anthropometric measurements and blood lipid-related indexes. The aim of this study was to examine the relationship between several anthropometric measurements and blood lipid-related indexes in MAFLD patients. This study was conducted among 123 MAFLD patients in a private University Hospital in Istanbul, Turkey, between 01.06.2021 - 30.12.2021. Anthropometric and biochemical measurements were taken from all patients. Hepatic steatosis was determined using ultrasonography. SPSS was used to analyze the data. Neck circumference (NC) was moderately associated with triglyceride glucose index (TyG) in both genders. It was found that there was a moderate correlation between NC and cardiometabolic index (CMI), triglyceride (TG), and triglyceride to high-density lipoprotein ratio (TG/HDL-C) in women, whereas it was weakly correlated with CMI index in men. Neck-to-height ratio (NHtR) was moderately associated with CMI, and TyG indexes in women, while it was weakly correlated with TyG index in men. There was a moderate association between waist-to-hip ratio (WHR) and low-density lipoprotein (LDL-C) in women. However, it was only weakly correlated with CMI index in men. It was observed that the waist-to-height ratio (WHtR) was only linked with TyG index in men. Additionally, the body mass index (BMI) and blood lipid-related indicators had no association. Our finding suggests that both NC and NHtR could be used to predict the risk of dyslipidemia in MAFLD, especially among women.