Development of bioactive PLA nanofiber wound dressings with Hypericum perforatum and zeolite

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dc.contributor.authorCaliskan, Seviye Nur
dc.contributor.authorFarrah, Yara
dc.contributor.authorDemircan, Nazlican
dc.contributor.authorYilmaz, Berke Veli
dc.contributor.authorAlaca, Yigit Furkan
dc.contributor.authorPilavci, Esra
dc.contributor.authorKanli, Zehra
dc.date.accessioned2025-11-16T19:33:49Z
dc.date.issued2026
dc.departmentİstanbul Medeniyet Üniversitesi
dc.description.abstractThis study presents the development of innovative wound dressings using Poly (Lactic Acid) (PLA) nanofibers functionalised with Hypericum perforatum (HP) extract and natural zeolite (ZEO). Nanofibers were fabricated via electrospinning and characterised. Results revealed that HP and ZEO significantly enhanced the thermal stability, mechanical strength, and biocompatibility of the nanofibers. When in vitro release of HP was analyzed, it was found to be finally released within 18 days. HP and ZEO together were increased the mechanical strength to the value of 1.84 +/- 0.53 MPa. This study highlights the synergy of natural bioactive compounds and sustainable materials in creating advanced wound care solutions.
dc.identifier.doi10.1016/j.matlet.2025.139384
dc.identifier.issn0167-577X
dc.identifier.issn1873-4979
dc.identifier.scopus2-s2.0-105014814717
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1016/j.matlet.2025.139384
dc.identifier.urihttps://hdl.handle.net/20.500.14730/15148
dc.identifier.volume403
dc.identifier.wosWOS:001567367900001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofMaterials Letters
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250302
dc.subjectElectrospinning
dc.subjectHypericum perforatum
dc.subjectWound healing
dc.titleDevelopment of bioactive PLA nanofiber wound dressings with Hypericum perforatum and zeolite
dc.typeArticle

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