The role of radiological imaging or masses in the prevascular mediastinum in clinical practice

dc.authoridProsch, Helmut/0000-0002-6119-6364
dc.contributor.authorProsch, Helmut
dc.contributor.authorRohrich, Sebastian
dc.contributor.authorTekin, Zeynep Nilufer
dc.contributor.authorEbner, Lukas
dc.date.accessioned2025-05-10T19:35:26Z
dc.date.issued2020
dc.departmentİstanbul Medeniyet Üniversitesi
dc.description.abstractTumors in the prevascular compartment of the mediastinum arc rare and imaging plays a major role in their detection, (differential) diagnosis, staging, and follow-up. The prevascular compartment is bordered anteriorly by the posterior aspect of the sternum, posteriorly by the ventral aspect of the pericardium, cranially by the thoracic outlet, and caudally by the diaphragm. In many cases, the diagnosis of a lesion in the prevascular compartment is an incidental finding either on chest radiograph (CR) or on computed tomography (CT) scans. The differential diagnosis of masses in the pre-vascular mediastinum include primarily tumors arising from the thymus or the thyroid gland, lymphomas and germ cell tumors. The differential diagnosis of mediastinal masses is primarily based on the location of the mass, its tissue composition (i.e., fat content, calcifications) and the age of the patient. The imaging method of choice is CT, as it combines a high spatial and temporal resolution with the ability to determine tissue composition and detect fluid components, as well as areas of fat and calcifications. MRI is used as a more specific problem-solving tool to discriminate solid lesions from cystic lesions or to provide evidence of minimal fat content in teratoma and thymic rebound. The role of PET/CT in the evaluation of tumors other than lymphomas in the prevascular compartment is still under discussion.
dc.description.sponsorshipStiftung Oskar Helene Heim, Berlin, Germany
dc.description.sponsorshipThis work was supported by an unrestricted grant from Stiftung Oskar Helene Heim, Berlin, Germany.
dc.identifier.doi10.21037/jtd-20-964
dc.identifier.endpage7597
dc.identifier.issn2072-1439
dc.identifier.issn2077-6624
dc.identifier.issue12
dc.identifier.pmid33447449
dc.identifier.scopusqualityQ2
dc.identifier.startpage7591
dc.identifier.urihttps://doi.org/10.21037/jtd-20-964
dc.identifier.urihttps://hdl.handle.net/20.500.14730/8872
dc.identifier.volume12
dc.identifier.wosWOS:000605343900054
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAme Publishing Company
dc.relation.ispartofJournal of Thoracic Disease
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250302
dc.subjectMediastinal tumors
dc.subjectthymoma
dc.subjectmediastinal teratoma
dc.subjectmediastinal lymphoma
dc.titleThe role of radiological imaging or masses in the prevascular mediastinum in clinical practice
dc.typeReview

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